Background: Measures of spatial intratumor heterogeneity are potentially important diagnostic biomarkers for cancer progression, proliferation, and response to therapy.Spatial relationships among cells including cancer and stromal cells in the tumor microenvironment (TME) are key contributors to heterogeneity.Methods: We demonstrate how to quantify
Transcarotid artery revascularization, or TCAR is an alternative to carotid endarterectomy for the surgical management of internal carotid artery stenosis.Not all patients with carotid disease are eligible for TCAR, as lesion anatomy must be compatible with current technology available for stent delivery.In this paper, we present two cases that uti
The wave energy converter (WEC) system, which extracts electricity through the relative heave motion of two concentric cylinders, comprises an inner cylinder and a torus-type outer cylinder sliding along the inner cylinder.To maximize the relative heave motion between two cylinders, the natural frequencies of the two cylinders must be precisely tun
In order to ensure joint operation of wind-PV-hydro complementary generation system with cascade hydro-power owned by multiple stakeholders, an equitable and efficient allocating mechanism for incremental benefit is of great importance.Firstly, rod brake the incremental benefit from joint operation is quantified for wind-PV-hydro complementary gene